diff --git a/runtime/queries/python/highlights.scm b/runtime/queries/python/highlights.scm
index 0a082f2fd..9f7d2790c 100644
--- a/runtime/queries/python/highlights.scm
+++ b/runtime/queries/python/highlights.scm
@@ -215,9 +215,11 @@
 [
   "and"
   "or"
+  "not in"
   "in"
   "not"
   "del"
+  "is not"
   "is"
 ] @keyword.operator